DSIP (DELTA SLEEP-INDUCING PEPTIDE)
Compound Overview
Delta Sleep-Inducing Peptide (DSIP) is a synthetic nonapeptide (nine-amino-acid peptide) originally isolated in 1977 from rabbit cerebral venous blood during studies investigating sleep physiology. Although its precise endogenous origin and receptor have not been definitively established, DSIP has become an important investigational peptide for studying neuropeptide signaling, neuroendocrine regulation, and sleep-related physiological processes.
DSIP has been extensively investigated in laboratory models to better understand its interactions with central nervous system signaling pathways, stress physiology, circadian regulation, hormonal modulation, and peptide pharmacology. Because its mechanism of action remains incompletely understood, it continues to serve as a valuable research tool for exploring peptide-mediated communication within the neuroendocrine system.
As an investigational peptide, DSIP supports research involving molecular neuroscience, peptide pharmacokinetics, neurobiology, cellular signaling, and structure-activity relationships. Ongoing studies continue to examine its biological properties in controlled experimental settings.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Lyophilized Powder |
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE) |
| Molecular Formula | C35H48N10O15 |
| Molecular Weight | 848.81 g/mol |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from moisture and light. |
| CAS Number | 62568-57-4 |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of DSIP (DELTA SLEEP-INDUCING PEPTIDE) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve peptide stability. For extended laboratory storage, freezing at −20°C or below is recommended. Protect the lyophilized peptide from moisture, excessive heat, and direct light. Avoid repeated freeze-thaw cycles following reconstitution, as these may reduce peptide stability. Allow the vial to equilibrate to room temperature before opening to minimize condensation, and always use sterile laboratory equipment together with appropriate aseptic laboratory techniques. This product is intended for use only by qualified research personnel operating in controlled laboratory environments.
Selected Scientific Literature
- Schoenenberger GA, Monnier M. Amino Acid Sequence and Synthesis of Delta Sleep-Inducing Peptide (DSIP). Proceedings of the National Academy of Sciences (PNAS).
- Graf MV, Kastin AJ. Delta Sleep-Inducing Peptide (DSIP): Pharmacological and Physiological Properties. Peptides.
- Monnier M, Schoenenberger GA. Delta Sleep-Inducing Peptide: Biological Activity and Experimental Studies. Experientia.
- Kastin AJ, Ehrensing RH, Schally AV, Coy DH. Improvement of Learning and Memory by Delta Sleep-Inducing Peptide. Pharmacology Biochemistry and Behavior.
Compare with related compounds
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| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| DSIP (DELTA SLEEP-INDUCING PEPTIDE) | 99% | 848.81 g/mol | 62568-57-4 |
| SELANK | 99% | 751.87 g/mol | 129954-34-3 |
| SEMAX | 99% | 813.87 g/mol | 80714-61-0 |
| CEREBROLYSIN | Standardized Peptide Preparation | — | 12656-61-0 |
| PINEALON | 99% | 418.40 g/mol | Not Assigned |
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