EPITALON (EPITHALON)
Compound Overview
Epitalon, also known as Epithalon, is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly (AEDG). It was developed as a synthetic analog of Epithalamin, a naturally occurring peptide complex isolated from the pineal gland. Epitalon has become an important investigational peptide for studying cellular biology, peptide pharmacology, and the molecular mechanisms associated with aging and genomic stability.
Researchers continue to investigate Epitalon in experimental models to better understand its interactions with telomerase regulation, cellular senescence, gene expression, oxidative stress, and circadian biology. It has been widely utilized as a research tool for exploring the molecular pathways involved in chromosomal stability, DNA protection, and cellular homeostasis.
As an investigational peptide, Epitalon supports laboratory research involving molecular biology, peptide engineering, pharmacokinetics, and structure-activity relationships. Ongoing studies continue to examine its biological properties and mechanisms of action in controlled experimental settings.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Lyophilized Powder |
| Sequence | Ala-Glu-Asp-Gly (AEDG) |
| Molecular Formula | C14H22N4O9 |
| Molecular Weight | 390.35 g/mol |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from moisture and light. |
| CAS Number | 307297-39-8 |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of EPITALON (EPITHALON) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt to preserve peptide stability. For extended laboratory storage, freezing at −20°C or below is recommended. Protect the lyophilized peptide from moisture, excessive heat, and direct light. Avoid repeated freeze-thaw cycles following reconstitution, as these may reduce peptide stability. Allow the vial to equilibrate to room temperature before opening to minimize condensation, and always use sterile laboratory equipment together with appropriate aseptic laboratory techniques. This product is intended for use only by qualified research personnel operating in controlled laboratory environments.
Selected Scientific Literature
- Khavinson V, Anisimov VN, Bartke A. Peptide Regulation of Gene Expression and Protein Synthesis During Aging. Current Pharmaceutical Design.
- Khavinson VK, Bondarev IE, Butyugin AV. Epitalon Activates Telomerase in Human Somatic Cells. Bulletin of Experimental Biology and Medicine.
- Anisimov VN, Khavinson VK. Synthetic Peptides and Their Potential Role in Aging Research. Advances in Gerontology.
- Khavinson VK, Linkova NS. Short Peptides as Regulators of Gene Expression and Cellular Homeostasis. Biochemistry (Moscow).
Compare with related compounds
Other compounds researchers commonly browse alongside EPITALON (EPITHALON) in Longevity & Mitochondrial.
| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| EPITALON (EPITHALON) | 99% | 390.35 g/mol | 307297-39-8 |
| SS-31 (ELAMIPRETIDE) | 99% | 639.79 g/mol | 736992-21-5 |
| MOTS-c | 99% | 2,174.6 g/mol | 1627580-64-6 |
| NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE) | 99% | 663.43 g/mol | 53-84-9 |
| HMG (HUMAN MENOPAUSAL GONADOTROPIN) | 99% | — | Not Applicable (Biological Gonadotropin Preparation) |
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