MT-II (MELANOTAN II)
Compound Overview
Melanotan II (MT-II) is a synthetic cyclic heptapeptide and analog of α-melanocyte-stimulating hormone (α-MSH). It functions primarily as a melanocortin receptor agonist, interacting with several melanocortin receptor subtypes, including MC1R, MC3R, MC4R, and MC5R. Its receptor activity has made MT-II an important research compound for investigating melanocortin signaling pathways, receptor pharmacology, and peptide-mediated cellular responses.
Researchers continue to study MT-II in laboratory settings to better understand the role of melanocortin receptors in pigmentation biology, neuroendocrine signaling, energy homeostasis, and receptor activation mechanisms. Its well-characterized pharmacological profile has made it a widely used reference compound in peptide and receptor research.
MT-II remains an important investigational tool for examining peptide stability, receptor selectivity, intracellular signaling pathways, and structure-activity relationships in experimental models.
Research Applications
Research applications are presented for educational and informational purposes only and do not imply approved therapeutic uses.
Product Specifications
| Purity | 99% |
| Appearance | White to Off-White Lyophilized Powder |
| Molecular Formula | C50H69N15O9 |
| Molecular Weight | 1,024.2 g/mol |
| Storage | Store refrigerated at 2–8°C (36–46°F). For extended laboratory storage, maintain at −20°C or below. Protect from light and moisture. |
| CAS Number | 121062-08-6 |
| Research Grade | Laboratory Research Use Only |
Available Sizes
Pricing: Inquire — contact our team for current pricing and availability.
Product Documentation
Every batch of MT-II (MELANOTAN II) is independently tested and assigned its own lot number. When you request documentation, include the product name and lot number printed on your vial so we can send the COA, HPLC, and MS data specific to the batch in your hand — not a generic reference sample. Request documentation →
Laboratory Handling
Store refrigerated immediately upon receipt and maintain recommended laboratory storage conditions to preserve peptide stability. For extended storage, freezing at −20°C or below is recommended. Protect the lyophilized peptide from moisture and prolonged exposure to light. Avoid repeated freeze-thaw cycles and allow the vial to reach room temperature before opening to minimize condensation. Handle using appropriate aseptic laboratory techniques and sterile equipment. This product is intended for use only by qualified research personnel operating in accordance with established laboratory protocols.
Selected Scientific Literature
- Hruby VJ, Wilkes BC, Hadley ME, et al. α-Melanotropin: The Minimal Active Sequence in the Frog Skin Bioassay. Journal of Medicinal Chemistry.
- Sawyer TK, Sanfilippo PJ, Hruby VJ, et al. 4-Norleucine, 7-D-Phenylalanine-α-MSH: A Highly Potent α-Melanocyte-Stimulating Hormone Analog. Peptides.
- Hadley ME, Dorr RT. Melanocortin Peptide Therapeutics: Historical Perspectives and Future Directions. Peptides.
Compare with related compounds
Other compounds researchers commonly browse alongside MT-II (MELANOTAN II) in Sexual Health & Pigmentation.
| Compound | Purity | Molecular Weight | CAS Number |
|---|---|---|---|
| MT-II (MELANOTAN II) | 99% | 1,024.2 g/mol | 121062-08-6 |
| MT-I (MELANOTAN I / AFAMELANOTIDE) | 99% | 1,646.84 g/mol | 75921-69-6 |
| PT-141 (BREMELANOTIDE) | 99% | 1,025.18 g/mol | 189691-06-3 |
| ALPROSTADIL (PROSTAGLANDIN E1) | 99% | 354.48 g/mol | 745-65-3 |
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